Searchable abstracts of presentations at key conferences in oncology

Oncology Abstracts

Published by BioScientifica

Page 1 of about 3 results

oa0001p021 | (1) | PacRim7

Estrogen receptor alpha controls gene expression via translational offsetting

Lorent Julie , Rebello Richard J , van Hoef Vincent , Lawrence Mitchell G , Szkop Krzysztof J , Kusnadi Eric , Samreen Baila , Balanathan Preetika , Scharmann Karin , Takizawa Itsuhiro , Leidel Sebastian A , Risbridger Gail P , Topisirovic Ivan , Larsson Ola , Furic Luc

Estrogen receptor alpha (ERα) activity is associated with increased cancer cell proliferation. Studies aiming to understand the impact of ERα on cancer-associated phenotypes have largely been limited to its transcriptional activity. Herein, we demonstrate that ERα coordinates its transcriptional output with selective modulation of mRNA translation. Importantly, translational perturbations caused by depletion of ERα largely manifest as ‘translational of...
0 shares

oa0001p042 | (1) | PacRim7

PARP inhibitor and CX-5461 combination therapy as a novel treatment strategy for castrate-resistant prostate cancer

Porter Laura H , Lawrence Mitchell G , Choo Nicholas K , Sandhu Shahneen , Wang Hong , Melbourne Urological Research Alliance (MURAL) , Pook David , Sanij Elaine , Pearson Richard B , Hannan Ross , Furic Luc , Taylor Renea A , Risbridger Gail P

Abstract unavailable....
0 shares

oa0001p031 | (1) | PacRim7

New combination therapies for castration-resistant prostate cancer

Lawrence Mitchell G , Porter Laura H , Obinata Daisuke , Sandhu Shahneen , Selth Luke A , Wong Stephen Q , Choo Nicholas , Pook David , Pezaro Carmel J , Goode David L , Clark Ashlee K , Papargiris Melissa , Toivanen Roxanne , Dehm Scott M , Melbourne Urological Research Alliance Scott M , CASCADE Scott M , kConfab Scott M , Thorne Heather , Tilley Wayne D , Pearson Richard B , Hannan Ross D , Murphy Declan G , Frydenberg Mark , Furic Luc , Taylor Renea A , Risbridger Gail P

Abstract unavailable....
0 shares

Published by BioScientifica

Oncology Abstracts
ISSN 2631-4657 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more