oa0001p023 | (1) | PacRim7
Wilson Gemma M
, Guild Barbara J
, Clarke Christine L
, Pathmanathan Nirmala
, Graham J Dinny
The establishment of mammographic screening programs has resulted in a striking increase in the incidence of ductal carcinoma in situ (DCIS), with DCIS accounting for approximately 20% of all new screen-detected breast cancers. An estimated 40% to 70% of DCIS lesions may progress to invasive disease if left untreated. This number is considerably reduced by treatment: surgical excision followed by radiation therapy is curative in over 95% of cases. However, of the DCIS...