oa0001p015 | (1) | PacRim7
Cursons Joseph
, Pillman Katherine A
, Scheer Kaitlin G
, Gregory Philip A
, Foroutan Momeneh
, Hediyeh-Zadeh Soroor
, Toubia John
, Crampin Edmund J
, Goodall Gregory J
, Bracken Cameron P
, Davis Melissa J
Epithelial-mesenchymal transition (EMT) and the reverse mesenchymal-epithelial transition (MET) are normal biological processes, however they are also thought to play a critical role in the progression and metastasis of cancers, including breast cancer. Cancer cells reactivate the gene expression programs of EMT and MET through a wide range of mechanisms, and better understanding of these regulatory processes will lead to the identification of therapeutically actionable target...